Pubblicazioni
2024
Bon C., Santulli C., De Cecco E., Codrich M., Narkiewicz J., Parisse P., Perissinotto F., Santoro C., Persichetti F., Legname G., Espinoza S., Gustincich S.
Neuronal haemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein
AD-PD 2024 - Alzheimer's & Parkinson's Diseases Conference
Poster
Conference
2023
D'Agostino S., Tettey M. A., Volpe M., Pierattini B., Ansaloni F., Lau P., Bon C., Peruzzo O., Braccia C., Armirotti A., Scarpato M., Damiani D., Di Carlo V., Carninci P., Santoro C., Persichetti F., Pandolfini L., Espinoza S., Zucchelli S., Sanges R., Gustincich S.
Internal Ribosome Entry Sites act as Effector Domain in linear and circular antisense long non-coding SINEUP RNAs
bioRxiv
Article
E-print Archive
2023
Bon C., Santulli C., De Cecco E., Codrich M., Narkiewicz J., Parisse P., Perissinotto F., Santoro C., Persichetti F., Legname G., Espinoza S., Gustincich S.
Neuronal haemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein
SINS 2023, Italian Society for Neuroscience
Poster
Conference
2023
Pierattini B., D'Agostino S., Bon C., Peruzzo O., Alendar A., Codino A., Ros G., Persichetti F., Sanges R., Carninci P., Santoro C., Espinoza S., Valentini P., Pandolfini L., Gustincich S.
SINEUP non-coding RNA activity depends on specific N6-methyladenosine nucleotides
Molecular Therapy - Nucleic Acids, vol. 32, pp. 402-414
2023
Nicoli A., Weber V., Bon C., Steuer A., Gustincich S., Gainetdinov R.R., Lang R., Espinoza S., Di Pizio A.
Structure-Based Discovery of Mouse Trace Amine-Associated Receptor 5 Antagonists
Journal of Chemical Information and Modeling, vol. 63, (no. 21), pp. 6667-6680
2022
Bon C., Chern T.-R., Cichero E., O'brien T.E., Gustincich S., Gainetdinov R.R., Espinoza S.
Discovery of Novel Trace Amine-Associated Receptor 5 (TAAR5) Antagonists Using a Deep Convolutional Neural Network
International Journal of Molecular Sciences, vol. 23, (no. 6)
2022
Maggi S., Bon C., Gustincich S., Tucci V., Gainetdinov R.R., Espinoza S.
Improved cognitive performance in trace amine-associated receptor 5 (TAAR5) knock-out mice
Scientific Reports, vol. 12, (no. 1)
2022
Bon C., Santulli C., De Cecco E., Codrich M., Narkiewicz J., Parisse P., Perissinotto F., Santoro C., Persichetti F., Legname G., Espinoza S., Gustincich S.
Neuronal haemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein
FENS Forum of Neuroscience
Poster
Conference
2022
Santulli C., Bon C., De Cecco E., Codrich M., Narkiewicz J., Parisse P., Perissinotto F., Santoro C., Persichetti F., Legname G., Espinoza S., Gustincich S.
Neuronal haemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein
Cell Death and Disease, vol. 13, (no. 12)
2022
Bon C., Pierattini B., Espinoza S., D Agostino S., Ros G., Peruzzo O., Persichetti F., Sanges R., Santoro C., Gustincich S.
SINEUPs: a novel toolbox for RNA-based therapy of neurodegenerative diseases
Società Italiana di Biofisica e Biologia Molecolare
Poster
Conference
2021
Espinoza S., Bon C., Valentini P., Pierattini B., Matey A.T., Damiani D., Pulcrano S., Sanges R., Persichetti F., Takahashi H., Carninci P., Santoro C., Cotella D., Gustincich S.
SINEUPs: A novel toolbox for RNA therapeutics
Essays in Biochemistry, vol. 65, (no. 4), pp. 775-789
2019
Bon C., Luffarelli R., Russo R., Fortuni S., Pierattini B., Santulli C., Fimiani C., Persichetti F., Cotella D., Mallamaci A., Santoro C., Carninci P., Espinoza S., Testi R., Zucchelli S., Condo I., Gustincich S.
SINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich's Ataxia
Nucleic Acids Research, vol. 47, (no. 20), pp. 10728-10743
2019
Fasolo F., Patrucco L., Volpe M., Bon C., Peano C., Mignone F., Carninci P., Persichetti F., Santoro C., Zucchelli S., Sblattero D., Sanges R., Cotella D., Gustincich S.
The RNA-binding protein ILF3 binds to transposable element sequences in sineup lncRNAs
FASEB Journal, vol. 33, (no. 12), pp. 13572-13589
2018
Bon C., Luffarelli R., Fortuni S., Zucchelli S., Condo I., Gustincich S.
SINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich’s ataxia.
RNA Therapeutics Conference
Poster
Conference
2018
Podbevsek P., Fasolo F., Bon C., Cimatti L., Reisser S., Carninci P., Bussi G., Zucchelli S., Plavec J., Gustincich S.
Structural determinants of the SINE B2 element embedded in the long non-coding RNA activator of translation AS Uchl1
Scientific Reports, vol. 8, (no. 1)